Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors
The application of induced pluripotent stem cells (iPSCs) in advanced therapies is increasing at pace, but concerns remain over their clinical safety profile.We report the first-ever application of hindigyanvishv.com doggybone DNA (dbDNA) vectors to generate human iPSCs.dbDNA vectors are closed-capped linear double-stranded DNA gene expression cass